SDCSB began in 2005 as the San Diego Consortium for Systems Biology to bring together scientists across disciplines and institutions, promote collaborative research and training, and to support the exchange of ideas and resources.
In 2010, we became one of the National Centers for Systems Biology funded by the National Institute of General Medical Sciences (NIGMS) (Grant #GM085764). SDCSB comprises activities in (i) scientific research, (ii) scientific outreach, and (iii) educational outreach.
We welcome you to participate in the revolution that is gripping the biological and biomedical sciences, catalyzed by unprecedented measurement capabilities and computational analysis and modeling tools. Start by exploring this website, participate in our workshops, symposia and research meetings, and let us know about good ideas for new research and outreach activities that SDCSB can support.
SDCSB Directors,
Alexander Hoffmann
Jeff Hasty
Trey Ideker
In a novel use of gene knockout technology, researchers at the University of California, San Diego School of Medicine tested the same gene inserted into 90 different locations in a yeast chromosome – and discovered that while the inserted gene never altered its surrounding chromatin landscape, differences in that immediate landscape measurably affected gene activity.
